Progress in Palladium-Catalyzed Synthesis of Pyrimidine Nucleoside Derivatives 钯催化合成嘧啶核苷衍生物的研究进展
Objective To investigate the clinical significances in prognosis of the expression of Pyrimidine Nucleoside Phosphorylase ( PyNPase) in primary hepatocellular carcinoma. 胸腺嘧啶或胸腺嘧啶核苷均不合格。目的初步探讨嘧啶核苷磷酸化酶在原发性肝癌中表达的临床预后意义。
The purine and pyrimidine may be complexed with a sugar to produce a nucleoside. 嘌呤和嘧啶可以同一个糖复合,产生一个核苷。
Lamivudine is a typical antivirus agent of pyrimidine nucleoside, mainly used for the treatment of hepatitis B. 拉米夫定是一种嘧啶核苷类抗病毒药物,主要用于慢性乙型肝炎的治疗。
Objective: To obtained the optimized fermentation conditions of reconbinant pyrimidine nucleoside phosphorylase ( PyNPase). 目的:优化嘧啶核苷磷酸化酶(PyNPase)基因工程菌的发酵条件。
The research and development of nucleoside anti-HIV drugs in recent years were reviewed. A number of pyrimidine nucleoside and purine nucleoside anti-HIV compounds were mainly introduced. Their mechanism of action and the strategy on research and development of them were also discussed. 综述近年来核苷类抗HIV药物的研究与开发,着重介绍若干嘧啶核苷类和嘌呤核苷类抗HIV化合物,并探讨其作用机制和该类药物的研发策略。
Dynamics Simulation of Rigid Body Movement of the α and α/ β Domains of Pyrimidine Nucleoside Phosphorylase 嘧啶核苷磷酸化酶的α和α/β结构域刚性移动的动力学模拟
Pyrimidine Nucleoside Phosphorylase and the Evaluation of Anticancer Drugs 嘧啶核苷磷酸化酶与抗癌药物治疗效果的评价
Thymidine phosphorylase is one of the pyrimidine nucleoside phosphorylase family, it is essential for synthesis and restriction of cell growth. 胸苷磷酸化酶(thymidinephosphorylase.TP)是嘧啶核苷磷酸化酶家族成员之一,是合成、限制细胞生长的必需酶。
Pyrimidine nucleoside phosphorylase ( PyNPase), a key enzyme in the pyrimidine salvage pathway, is broadly distributed in various microorganism and mammalian cells. 嘧啶核苷磷酸化酶(PyNPase)是嘧啶核苷补救代谢途径中的关键酶,广泛分布于微生物及动物组织细胞中。